Etiologic classification of Diabetes Mellitus :

Etiologic classification of DM  :

• Type 1 Diabetes 

1.   Immune Mediated
2.    Idiopathic

• Type 2 Diabetes
• Gestational  Diabetes Mellitus
• Others:

1. Genetic defects of β-cell function ( MODY 3,1,2, TND )
2. Genetic defects in insulin action  (Leprechaunism,Rabson–Mendenhall sd)
3. Diseases of the exocrine pancreas (Pancreatitis, Trauma , Neoplasia, CF)
4. Endocrinopathies (Acromegaly, Cushing’s, Hyperthyroidism ,Pheochromo..)
5. Drug or chemical induced ( Vacor, Glucocorticoids, Thiazides)
6. Infections (Congenital rubella, CMV )
7. Uncommon forms of immune-mediated diabetes (Stiff-man syndrome)
8. Other genetic syndromes sometimes associated with diabetes ( XO, XXY, Trisomy 21, etc)